Landscape of enhancer disruption and functional screen in melanoma cells
Landscape of enhancer disruption and functional screen in melanoma cells
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Author / Creator
Wang, Zhao , Luo, Menghan , Liang, Qian , Zhao, Ke , Hu, Yuelin , Wang, Wei , Feng, Xiangling , Hu, Bolang , Teng, Jianjin , You, Tianyi , Li, Ran , Bao, Zhengkai , Pan, Wenhao , Yang, Tielong , Zhang, Chao , Li, Ting , Dong, Xiaobao , Yi, Xianfu , Liu, Ben , Zhao, Li , Li, Miaoxin , Chen, Kexin , Song, Weihong , Yang, Jilong and Li, Mulin Jun
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The high mutation rate throughout the entire melanoma genome presents a major challenge in stratifying true driver events from the background mutations. Numerous recurrent non-coding alterations, such as those in enhancers, can shape tumor evolution, thereby emphasizing the importance in systematically deciphering enhancer disruptions in melanoma.<...
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Full title
Landscape of enhancer disruption and functional screen in melanoma cells
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TN_cdi_doaj_primary_oai_doaj_org_article_ea2c5d7f313e4e34877e64882a16ffd9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea2c5d7f313e4e34877e64882a16ffd9
Other Identifiers
ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-023-03087-5
