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Retained introns in long RNA-seq reads are not reliably detected in sample-matched short reads

Retained introns in long RNA-seq reads are not reliably detected in sample-matched short reads

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea62db3678a941dabe74f0c088a5f2e6

Retained introns in long RNA-seq reads are not reliably detected in sample-matched short reads

About this item

Full title

Retained introns in long RNA-seq reads are not reliably detected in sample-matched short reads

Publisher

England: BioMed Central

Journal title

Genome Biology, 2022-11, Vol.23 (1), p.240-240, Article 240

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

There is growing interest in retained introns in a variety of disease contexts including cancer and aging. Many software tools have been developed to detect retained introns from short RNA-seq reads, but reliable detection is complicated by overlapping genes and transcripts as well as the presence of unprocessed or partially processed RNAs.
We c...

Alternative Titles

Full title

Retained introns in long RNA-seq reads are not reliably detected in sample-matched short reads

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ea62db3678a941dabe74f0c088a5f2e6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea62db3678a941dabe74f0c088a5f2e6

Other Identifiers

ISSN

1474-760X,1474-7596

E-ISSN

1474-760X

DOI

10.1186/s13059-022-02789-6

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