The loss of DLG2 isoform 7/8, but not isoform 2, is critical in advanced staged neuroblastoma
The loss of DLG2 isoform 7/8, but not isoform 2, is critical in advanced staged neuroblastoma
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Neuroblastoma is a childhood neural crest tumor showing large clinical and genetic heterogeneity, one form displaying 11q-deletion is very aggressive. It has been shown that 11q-deletion results in decreased expression of DLG2, a gene residing in the deleted region. DLG2 has a number of different isoforms with the main difference is the presence or...
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The loss of DLG2 isoform 7/8, but not isoform 2, is critical in advanced staged neuroblastoma
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TN_cdi_doaj_primary_oai_doaj_org_article_ea7db444735f492ebc7edfa8092a4fba
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea7db444735f492ebc7edfa8092a4fba
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ISSN
1475-2867
E-ISSN
1475-2867
DOI
10.1186/s12935-021-01851-w