Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models...
Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In type1 diabetes (T1D) autoreactive T-cells infiltrate the islets of Langerhans, depleting insulin-secreting β-cells (insulitis). Insulitis arises during an asymptomatic phase, prior to clinical diagnosis of T1D. Methods to diagnose insulitis and β-cell mass changes during this asymptomatic phase are limited, precluding early therapeutic intervent...
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Full title
Contrast-enhanced ultrasound with sub-micron sized contrast agents detects insulitis in mouse models of type1 diabetes
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TN_cdi_doaj_primary_oai_doaj_org_article_ea834bcc10ac40038a26340fb8b2edc0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea834bcc10ac40038a26340fb8b2edc0
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15957-8
