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Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D...

Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea8477d4bc2143b1b6b2e40b1317c4e3

Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D ovarian and breast cancer in vitro models

About this item

Full title

Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D ovarian and breast cancer in vitro models

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-04, Vol.12 (1), p.6548-6548, Article 6548

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Long-term treatment of cancer with chemotherapeutics leads to the development of resistant forms that reduce treatment options. The main associated mechanism is the overexpression of transport proteins, particularly P-glycoprotein (P-gp, ABCB1). In this study, we have tested the anticancer and multidrug resistance (MDR) modulation activity of 15 se...

Alternative Titles

Full title

Ketone-selenoesters as potential anticancer and multidrug resistance modulation agents in 2D and 3D ovarian and breast cancer in vitro models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ea8477d4bc2143b1b6b2e40b1317c4e3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea8477d4bc2143b1b6b2e40b1317c4e3

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-10311-y

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