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Antagonism of ALAS1 by the Measles Virus V protein contributes to degradation of the mitochondrial n...

Antagonism of ALAS1 by the Measles Virus V protein contributes to degradation of the mitochondrial n...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea866ec9f1a34fd2a802d07e69f6149a

Antagonism of ALAS1 by the Measles Virus V protein contributes to degradation of the mitochondrial network and promotes interferon response

About this item

Full title

Antagonism of ALAS1 by the Measles Virus V protein contributes to degradation of the mitochondrial network and promotes interferon response

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2023-02, Vol.19 (2), p.e1011170-e1011170

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Viruses have evolved countless mechanisms to subvert and impair the host innate immune response. Measles virus (MeV), an enveloped, non-segmented, negative-strand RNA virus, alters the interferon response through different mechanisms, yet no viral protein has been described as directly targeting mitochondria. Among the crucial mitochondrial enzymes...

Alternative Titles

Full title

Antagonism of ALAS1 by the Measles Virus V protein contributes to degradation of the mitochondrial network and promotes interferon response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ea866ec9f1a34fd2a802d07e69f6149a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea866ec9f1a34fd2a802d07e69f6149a

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1011170

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