Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells
Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Infection of specific pathogen-free mice with lymphocytic choriomeningitis virus (LCMV) is a widely used model to study antiviral T-cell immunity. Infections in the real world, however, are often accompanied by coinfections with unrelated pathogens. Here we show that in mice, systemic coinfection with
E. coli
suppresses the LCMV-specific cyto...
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Full title
Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells
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TN_cdi_doaj_primary_oai_doaj_org_article_ea8d1ad39a4f4d37855579d39f274857
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea8d1ad39a4f4d37855579d39f274857
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06609-z
