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A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea97ba56f1764b518e534e1063bf2e68

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Approximately a quarter of the human genome consists of gene deserts, large regions devoid of genes often located adjacent to developmental genes and thought to contribute to their regulation. However, defining the regulatory functions embedded within these deserts is challenging due to their large size. Here, we explore the
cis
-regulatory a...

Alternative Titles

Full title

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ea97ba56f1764b518e534e1063bf2e68

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea97ba56f1764b518e534e1063bf2e68

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-53009-7

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