A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
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Author / Creator
Abassah-Oppong, Samuel , Zoia, Matteo , Mannion, Brandon J. , Rouco, Raquel , Tissières, Virginie , Spurrell, Cailyn H. , Roland, Virginia , Darbellay, Fabrice , Itum, Anja , Gamart, Julie , Festa-Daroux, Tabitha A. , Sullivan, Carly S. , Kosicki, Michael , Rodríguez-Carballo, Eddie , Fukuda-Yuzawa, Yoko , Hunter, Riana D. , Novak, Catherine S. , Plajzer-Frick, Ingrid , Tran, Stella , Akiyama, Jennifer A. , Dickel, Diane E. , Lopez-Rios, Javier , Barozzi, Iros , Andrey, Guillaume , Visel, Axel , Pennacchio, Len A. , Cobb, John , Osterwalder, Marco and Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Approximately a quarter of the human genome consists of gene deserts, large regions devoid of genes often located adjacent to developmental genes and thought to contribute to their regulation. However, defining the regulatory functions embedded within these deserts is challenging due to their large size. Here, we explore the
cis
-regulatory a...
Alternative Titles
Full title
A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
Authors, Artists and Contributors
Author / Creator
Zoia, Matteo
Mannion, Brandon J.
Rouco, Raquel
Tissières, Virginie
Spurrell, Cailyn H.
Roland, Virginia
Darbellay, Fabrice
Itum, Anja
Gamart, Julie
Festa-Daroux, Tabitha A.
Sullivan, Carly S.
Kosicki, Michael
Rodríguez-Carballo, Eddie
Fukuda-Yuzawa, Yoko
Hunter, Riana D.
Novak, Catherine S.
Plajzer-Frick, Ingrid
Tran, Stella
Akiyama, Jennifer A.
Dickel, Diane E.
Lopez-Rios, Javier
Barozzi, Iros
Andrey, Guillaume
Visel, Axel
Pennacchio, Len A.
Cobb, John
Osterwalder, Marco
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ea97ba56f1764b518e534e1063bf2e68
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea97ba56f1764b518e534e1063bf2e68
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-53009-7
