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Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psorias...

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psorias...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea97f7082ce74177a2af8db079fd79c4

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

About this item

Full title

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-01, Vol.11 (1), p.105-105, Article 105

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Psoriasis is an inflammatory skin disease with strong neutrophil (PMN) infiltration and high levels of the antimicrobial peptide, LL37. LL37 in complex with DNA and RNA is thought to initiate disease exacerbation via plasmacytoid dendritic cells. However, the source of nucleic acids supposed to start this initial inflammatory event remains unknown....

Alternative Titles

Full title

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ea97f7082ce74177a2af8db079fd79c4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea97f7082ce74177a2af8db079fd79c4

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13756-4

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