Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psorias...
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis
About this item
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Author / Creator
Herster, Franziska , Bittner, Zsofia , Archer, Nathan K. , Dickhöfer, Sabine , Eisel, David , Eigenbrod, Tatjana , Knorpp, Thomas , Schneiderhan-Marra, Nicole , Löffler, Markus W. , Kalbacher, Hubert , Vierbuchen, Tim , Heine, Holger , Miller, Lloyd S. , Hartl, Dominik , Freund, Lukas , Schäkel, Knut , Heister, Martin , Ghoreschi, Kamran and Weber, Alexander N. R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Psoriasis is an inflammatory skin disease with strong neutrophil (PMN) infiltration and high levels of the antimicrobial peptide, LL37. LL37 in complex with DNA and RNA is thought to initiate disease exacerbation via plasmacytoid dendritic cells. However, the source of nucleic acids supposed to start this initial inflammatory event remains unknown....
Alternative Titles
Full title
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis
Authors, Artists and Contributors
Author / Creator
Bittner, Zsofia
Archer, Nathan K.
Dickhöfer, Sabine
Eisel, David
Eigenbrod, Tatjana
Knorpp, Thomas
Schneiderhan-Marra, Nicole
Löffler, Markus W.
Kalbacher, Hubert
Vierbuchen, Tim
Heine, Holger
Miller, Lloyd S.
Hartl, Dominik
Freund, Lukas
Schäkel, Knut
Heister, Martin
Ghoreschi, Kamran
Weber, Alexander N. R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ea97f7082ce74177a2af8db079fd79c4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ea97f7082ce74177a2af8db079fd79c4
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13756-4