The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences...
The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation
About this item
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Author / Creator
Morrissey, Maria E. , Byrne, Róisín , Nulty, Celina , McCabe, Niamh H. , Lynam-Lennon, Niamh , Butler, Clare T. , Kennedy, Susan , O’Toole, Dermot , Larkin, John , McCormick, Paul , Mehigan, Brian , Cathcart, Mary-Clare , Lysaght, Joanne , Reynolds, John V. , Ryan, Elizabeth J. , Dunne, Margaret R. and O’Sullivan, Jacintha
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Only 10-30% of oesophageal and rectal adenocarcinoma patients treated with neoadjuvant chemoradiotherapy have a complete pathological response. Inflammatory and angiogenic mediators in the tumour microenvironment (TME) may enable evasion of anti-tumour immune responses.
The TME influence on infiltrating dendritic cells (DCs) was modelled by trea...
Alternative Titles
Full title
The tumour microenvironment of the upper and lower gastrointestinal tract differentially influences dendritic cell maturation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_eac61d4bd7544b4db891309c642d064c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eac61d4bd7544b4db891309c642d064c
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-020-07012-y
