LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impa...
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy
About this item
Full title
Author / Creator
Pascual-García, Mónica , Bonfill-Teixidor, Ester , Planas-Rigol, Ester , Rubio-Perez, Carlota , Iurlaro, Raffaella , Arias, Alexandra , Cuartas, Isabel , Sala-Hojman, Ada , Escudero, Laura , Martínez-Ricarte, Francisco , Huber-Ruano, Isabel , Nuciforo, Paolo , Pedrosa, Leire , Marques, Carolina , Braña, Irene , Garralda, Elena , Vieito, María , Squatrito, Massimo , Pineda, Estela , Graus, Francesc , Espejo, Carmen , Sahuquillo, Juan , Tabernero, Josep and Seoane, Joan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Cancer response to immunotherapy depends on the infiltration of CD8
+
T cells and the presence of tumor-associated macrophages within tumors. Still, little is known about the determinants of these factors. We show that LIF assumes a crucial role in the regulation of CD8
+
T cell tumor infiltration, while promoting the presence of protum...
Alternative Titles
Full title
LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy
Authors, Artists and Contributors
Author / Creator
Bonfill-Teixidor, Ester
Planas-Rigol, Ester
Rubio-Perez, Carlota
Iurlaro, Raffaella
Arias, Alexandra
Cuartas, Isabel
Sala-Hojman, Ada
Escudero, Laura
Martínez-Ricarte, Francisco
Huber-Ruano, Isabel
Nuciforo, Paolo
Pedrosa, Leire
Marques, Carolina
Braña, Irene
Garralda, Elena
Vieito, María
Squatrito, Massimo
Pineda, Estela
Graus, Francesc
Espejo, Carmen
Sahuquillo, Juan
Tabernero, Josep
Seoane, Joan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_eafd754e38d148f4af2177cb43fd4fa5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eafd754e38d148f4af2177cb43fd4fa5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10369-9
