Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy
Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy
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Author / Creator
Niogret, Julie , Berger, Hélène , Rebe, Cédric , Mary, Romain , Ballot, Elise , Truntzer, Caroline , Thibaudin, Marion , Derangère, Valentin , Hibos, Christophe , Hampe, Léa , Rageot, David , Accogli, Théo , Joubert, Philippe , Routy, Bertrand , Harker, James , Vegran, Frederique , Ghiringhelli, Francois and Chalmin, Fanny
Publisher
England: BMJ Publishing Group Ltd
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Language
English
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Publisher
England: BMJ Publishing Group Ltd
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Contents
BackgroundT follicular helper cells (Tfh) are essential to shape B cell response during germinal center formation. Tfh accumulation has been reported in various human cancers, with positive or negative prognostic roles. However, the mechanisms explaining the accumulation of Tfh and their role in cancer remain obscure.MethodsIn vitro differentiated...
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Full title
Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy
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TN_cdi_doaj_primary_oai_doaj_org_article_eb04733954c348f69ad8e9ceaa3f46ea
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eb04733954c348f69ad8e9ceaa3f46ea
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-002157
