Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesion...
Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors
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Author / Creator
Kang, Minsu , Ahn, Soomin , Kim, Ji-Won , Lee, Sejoon , Ahn, Soyeon , Lee, Ju Hyun , Youk, Jeonghwan , Kim, Haesook T , Kim, Kui-Jin , Suh, Koung Jin , Lee, Jun Suh , Kim, Se Hyun , Kim, Jin Won , Kim, Yu Jung , Lee, Keun-Wook , Yoon, Yoo-Seok , Kim, Jee Hyun , Chung, Jin-Haeng , Han, Ho-Seong and Lee, Jong Seok
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Scope and Contents
Contents
We aimed to elucidate the evolutionary trajectories of gallbladder adenocarcinoma (GBAC) using multi-regional and longitudinal tumor samples. Using whole-exome sequencing data, we constructed phylogenetic trees in each patient and analyzed mutational signatures. A total of 11 patients including 2 rapid autopsy cases were enrolled. The most frequent...
Alternative Titles
Full title
Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors
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TN_cdi_doaj_primary_oai_doaj_org_article_eb1e776b7b494318b86d6c03670cbe69
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eb1e776b7b494318b86d6c03670cbe69
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.78636
