Single-cell sequencing of a novel model of neonatal bile duct ligation in mice identifies macrophage...
Single-cell sequencing of a novel model of neonatal bile duct ligation in mice identifies macrophage heterogeneity in obstructive cholestasis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Macrophages (MΦ) play a role in neonatal etiologies of obstructive cholestasis, however, the role for precise MΦ subsets remains poorly defined. We developed a neonatal murine model of bile duct ligation (BDL) to characterize etiology-specific differences in neonatal cholestatic MΦ polarization. Neonatal BDL surgery was performed on female BALB/c m...
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Single-cell sequencing of a novel model of neonatal bile duct ligation in mice identifies macrophage heterogeneity in obstructive cholestasis
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TN_cdi_doaj_primary_oai_doaj_org_article_eb2124bbc14840b0a30e011ad44439db
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eb2124bbc14840b0a30e011ad44439db
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-41207-0
