ADuLT: An efficient and robust time-to-event GWAS
ADuLT: An efficient and robust time-to-event GWAS
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Author / Creator
Pedersen, Emil M. , Agerbo, Esben , Plana-Ripoll, Oleguer , Steinbach, Jette , Krebs, Morten D. , Hougaard, David M. , Werge, Thomas , Nordentoft, Merete , Børglum, Anders D. , Musliner, Katherine L. , Ganna, Andrea , Schork, Andrew J. , Mortensen, Preben B. , McGrath, John J. , Privé, Florian and Vilhjálmsson, Bjarni J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Proportional hazards models have been proposed to analyse time-to-event phenotypes in genome-wide association studies (GWAS). However, little is known about the ability of proportional hazards models to identify genetic associations under different generative models and when ascertainment is present. Here we propose the age-dependent liability thre...
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Full title
ADuLT: An efficient and robust time-to-event GWAS
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TN_cdi_doaj_primary_oai_doaj_org_article_eb3d95affd73451ea109b0d277fe474f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eb3d95affd73451ea109b0d277fe474f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-41210-z
