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Actionability of HER2-amplified circulating tumor cells in HER2-negative metastatic breast cancer: t...

Actionability of HER2-amplified circulating tumor cells in HER2-negative metastatic breast cancer: t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eb8133670a8c471b9655035877df2e22

Actionability of HER2-amplified circulating tumor cells in HER2-negative metastatic breast cancer: the CirCe T-DM1 trial

About this item

Full title

Actionability of HER2-amplified circulating tumor cells in HER2-negative metastatic breast cancer: the CirCe T-DM1 trial

Publisher

England: BioMed Central Ltd

Journal title

Breast cancer research : BCR, 2019-11, Vol.21 (1), p.121-121, Article 121

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

In this prospective phase 2 trial, we assessed the efficacy of trastuzumab-emtansine (T-DM1) in HER2-negative metastatic breast cancer (MBC) patients with HER2-positive CTC.
Main inclusion criteria for screening were as follows: women with HER2-negative MBC treated with ≥ 2 prior lines of chemotherapy and measurable disease. CTC with a HER2/CEP1...

Alternative Titles

Full title

Actionability of HER2-amplified circulating tumor cells in HER2-negative metastatic breast cancer: the CirCe T-DM1 trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_eb8133670a8c471b9655035877df2e22

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eb8133670a8c471b9655035877df2e22

Other Identifiers

ISSN

1465-542X,1465-5411

E-ISSN

1465-542X

DOI

10.1186/s13058-019-1215-z

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