Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-...
Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation
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Author / Creator
Qi, Yadong , He, Jiamin , Zhang, Yawen , Ge, Qiwei , Wang, Qiwen , Chen, Luyi , Xu, Jilei , Wang, Lan , Chen, Xueqin , Jia, Dingjiacheng , Lin, Yifeng , Xu, Chaochao , Zhang, Ying , Hou, Tongyao , Si, Jianmin , Chen, Shujie and Wang, Liangjing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Declined numbers and weakened functions of intestinal stem cells (ISCs) impair the integrity of the intestinal epithelium during aging. However, the impact of intestinal microbiota on ISCs in this process is unclear. Here, using premature aging mice (telomerase RNA component knockout,
Terc
−/−
), natural aging mice, and in vitro colonoid m...
Alternative Titles
Full title
Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_eb9319dbdbb04562aafe294c9263c249
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_eb9319dbdbb04562aafe294c9263c249
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-41827-0
