A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2...
A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant
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Author / Creator
Chiu, Man Chun , Li, Cun , Liu, Xiaojuan , Yu, Yifei , Huang, Jingjing , Wan, Zhixin , Xiao, Ding , Chu, Hin , Cai, Jian-Piao , Zhou, Biao , Sit, Ko-Yung , Au, Wing-Kuk , Wong, Kenneth Kak-Yuen , Li, Gang , Chan, Jasper Fuk-Woo , To, Kelvin Kai-Wang , Chen, Zhiwei , Jiang, Shibo , Clevers, Hans , Yuen, Kwok Yung and Zhou, Jie
Publisher
Singapore: Springer Nature Singapore
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Language
English
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Publisher
Singapore: Springer Nature Singapore
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Contents
The airways and alveoli of the human respiratory tract are lined by two distinct types of epithelium, which are the primary targets of respiratory viruses. We previously established long-term expanding human lung epithelial organoids from lung tissues and developed a ‘proximal’ differentiation protocol to generate mucociliary airway organoids. Howe...
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Full title
A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variant
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TN_cdi_doaj_primary_oai_doaj_org_article_ebb0d7e4764e47428c490452e1a4e7e0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ebb0d7e4764e47428c490452e1a4e7e0
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ISSN
2056-5968
E-ISSN
2056-5968
DOI
10.1038/s41421-022-00422-1
