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System-agnostic prediction of pharmaceutical excipient miscibility via computing-as-a-service and ex...

System-agnostic prediction of pharmaceutical excipient miscibility via computing-as-a-service and ex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ebb3bc60dddf4410a21bada1ce4336df

System-agnostic prediction of pharmaceutical excipient miscibility via computing-as-a-service and experimental validation

About this item

Full title

System-agnostic prediction of pharmaceutical excipient miscibility via computing-as-a-service and experimental validation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-07, Vol.14 (1), p.15106-10, Article 15106

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

We applied computing-as-a-service to the unattended system-agnostic miscibility prediction of the pharmaceutical surfactants, Vitamin E TPGS and Tween 80, with Copovidone VA64 polymer at temperature relevant for the pharmaceutical hot melt extrusion process. The computations were performed in lieu of running exhaustive hot melt extrusion experiment...

Alternative Titles

Full title

System-agnostic prediction of pharmaceutical excipient miscibility via computing-as-a-service and experimental validation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ebb3bc60dddf4410a21bada1ce4336df

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ebb3bc60dddf4410a21bada1ce4336df

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-65978-2

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