VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart
VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart
About this item
Full title
Author / Creator
Kivelä, Riikka , Bry, Maija , Robciuc, Marius R , Räsänen, Markus , Taavitsainen, Miia , Silvola, Johanna MU , Saraste, Antti , Hulmi, Juha J , Anisimov, Andrey , Mäyränpää, Mikko I , Lindeman, Jan H , Eklund, Lauri , Hellberg, Sanna , Hlushchuk, Ruslan , Zhuang, Zhen W , Simons, Michael , Djonov, Valentin , Knuuti, Juhani , Mervaala, Eero and Alitalo, Kari
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Angiogenic growth factors have recently been linked to tissue metabolism. We have used genetic gain‐ and loss‐of function models to elucidate the effects and mechanisms of action of vascular endothelial growth factor‐B (VEGF‐B) in the heart. A cardiomyocyte‐specific VEGF‐B transgene induced an expanded coronary arterial tree and reprogramming of ca...
Alternative Titles
Full title
VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart
Authors, Artists and Contributors
Author / Creator
Bry, Maija
Robciuc, Marius R
Räsänen, Markus
Taavitsainen, Miia
Silvola, Johanna MU
Saraste, Antti
Hulmi, Juha J
Anisimov, Andrey
Mäyränpää, Mikko I
Lindeman, Jan H
Eklund, Lauri
Hellberg, Sanna
Hlushchuk, Ruslan
Zhuang, Zhen W
Simons, Michael
Djonov, Valentin
Knuuti, Juhani
Mervaala, Eero
Alitalo, Kari
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ebec774a221a4674a5d3e1c1b7a80b29
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ebec774a221a4674a5d3e1c1b7a80b29
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.1002/emmm.201303147
