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High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroin...

High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ebf58f4e1d3f4998b8f08e4ddf92213b

High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease

About this item

Full title

High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease

Publisher

England: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2021-07, Vol.18 (1), p.166-24, Article 166

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Differentiating infiltrating myeloid cells from resident microglia in neuroinflammatory disease is challenging, because bone marrow-derived inflammatory monocytes infiltrating the inflamed brain adopt a 'microglia-like' phenotype. This precludes the accurate identification of either cell type without genetic manipulation, which is important to unde...

Alternative Titles

Full title

High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ebf58f4e1d3f4998b8f08e4ddf92213b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ebf58f4e1d3f4998b8f08e4ddf92213b

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-021-02214-y

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