Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug...
Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans
About this item
Full title
Author / Creator
Ravindra, Kodihalli C. , Vaidya, Vishal S. , Wang, Zhenyu , Federspiel, Joel D. , Virgen-Slane, Richard , Everley, Robert A. , Grove, Jane I. , Stephens, Camilla , Ocana, Mireia F. , Robles-Díaz, Mercedes , Isabel Lucena, M. , Andrade, Raul J. , Atallah, Edmond , Gerbes, Alexander L. , Weber, Sabine , Cortez-Pinto, Helena , Fowell, Andrew J. , Hussaini, Hyder , Bjornsson, Einar S. , Patel, Janisha , Stirnimann, Guido , Verma, Sumita , Elsharkawy, Ahmed M. , Griffiths, William J. H. , Hyde, Craig , Dear, James W. , Aithal, Guruprasad P. and Ramaiah, Shashi K.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Diagnosis of drug-induced liver injury (DILI) and its distinction from other liver diseases are significant challenges in drug development and clinical practice. Here, we identify, confirm, and replicate the biomarker performance characteristics of candidate proteins in patients with DILI at onset (DO;
n
= 133) and follow-up (
n
= 120...
Alternative Titles
Full title
Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans
Authors, Artists and Contributors
Author / Creator
Vaidya, Vishal S.
Wang, Zhenyu
Federspiel, Joel D.
Virgen-Slane, Richard
Everley, Robert A.
Grove, Jane I.
Stephens, Camilla
Ocana, Mireia F.
Robles-Díaz, Mercedes
Isabel Lucena, M.
Andrade, Raul J.
Atallah, Edmond
Gerbes, Alexander L.
Weber, Sabine
Cortez-Pinto, Helena
Fowell, Andrew J.
Hussaini, Hyder
Bjornsson, Einar S.
Patel, Janisha
Stirnimann, Guido
Verma, Sumita
Elsharkawy, Ahmed M.
Griffiths, William J. H.
Hyde, Craig
Dear, James W.
Aithal, Guruprasad P.
Ramaiah, Shashi K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ec3315a517864777bd5bdde19a8b8aa2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec3315a517864777bd5bdde19a8b8aa2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-36858-6
