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Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza viru...

Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza viru...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec3fea68586d403ca7cbe0a5ebb446e7

Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza virus in vivo

About this item

Full title

Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza virus in vivo

Publisher

New Zealand: Dove Medical Press Limited

Journal title

Drug design, development and therapy, 2019-04, Vol.13, p.1059-1068

Language

English

Formats

Publication information

Publisher

New Zealand: Dove Medical Press Limited

More information

Scope and Contents

Contents

In this study, we report on the development of an effective delivery system for siRNAs; a novel cell-penetrating peptide (CPP), T9(dR), obtained from transportan (TP), was used for in vivo and in vitro testing.
In this study, toxicity of T9(dR) and TP and efficient delivery of siRNA were tested in 293T, MDCK, RAW, and A549 cells. Furthermore, T9...

Alternative Titles

Full title

Transportan-derived cell-penetrating peptide delivers siRNA to inhibit replication of influenza virus in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ec3fea68586d403ca7cbe0a5ebb446e7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec3fea68586d403ca7cbe0a5ebb446e7

Other Identifiers

ISSN

1177-8881

E-ISSN

1177-8881

DOI

10.2147/DDDT.S195481

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