In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell...
In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche
About this item
Full title
Author / Creator
Wang, Chao , Rabadan Ros, Ruben , Martinez-Redondo, Paloma , Ma, Zaijun , Shi, Lei , Xue, Yuan , Guillen-Guillen, Isabel , Huang, Ling , Hishida, Tomoaki , Liao, Hsin-Kai , Nuñez Delicado, Estrella , Rodriguez Esteban, Concepcion , Guillen-Garcia, Pedro , Reddy, Pradeep and Izpisua Belmonte, Juan Carlos
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Short-term, systemic expression of the Yamanaka reprogramming factors (
Oct-3/4
,
Sox2
,
Klf4
and
c-Myc
[OSKM]) has been shown to rejuvenate aging cells and promote tissue regeneration in vivo. However, the mechanisms by which OSKM promotes tissue regeneration are unknown. In this work, we focus on a specific tissue and demo...
Alternative Titles
Full title
In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ec46029f8e914da49e6eeddd4f0bc4ed
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec46029f8e914da49e6eeddd4f0bc4ed
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23353-z
