A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic auto...
A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity
About this item
Full title
Author / Creator
Ooi, Joshua D. , Jiang, Jhih-Hang , Eggenhuizen, Peter J. , Chua, Ling L. , van Timmeren, Mirjan , Loh, Khai L. , O’Sullivan, Kim M. , Gan, Poh Y. , Zhong, Yong , Tsyganov, Kirill , Shochet, Lani R. , Ryan, Jessica , Stegeman, Coen A. , Fugger, Lars , Reid, Hugh H. , Rossjohn, Jamie , Heeringa, Peter , Holdsworth, Stephen R. , Peleg, Anton Y. and Kitching, A. Richard
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Autoreactivity to myeloperoxidase (MPO) causes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), with rapidly progressive glomerulonephritis. Here, we show that a
Staphylococcus aureus
peptide, homologous to an immunodominant MPO T-cell epitope (MPO
409–428
), can induce anti-MPO autoimmunity. The peptide (6PGD
Alternative Titles
Full title
A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity
Authors, Artists and Contributors
Author / Creator
Jiang, Jhih-Hang
Eggenhuizen, Peter J.
Chua, Ling L.
van Timmeren, Mirjan
Loh, Khai L.
O’Sullivan, Kim M.
Gan, Poh Y.
Zhong, Yong
Tsyganov, Kirill
Shochet, Lani R.
Ryan, Jessica
Stegeman, Coen A.
Fugger, Lars
Reid, Hugh H.
Rossjohn, Jamie
Heeringa, Peter
Holdsworth, Stephen R.
Peleg, Anton Y.
Kitching, A. Richard
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ec5422e66a47466790d6d136a48ebe74
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec5422e66a47466790d6d136a48ebe74
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11255-0
