Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism
Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism
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Author / Creator
Duethorn, Binyamin , Groll, Fabian , Rieger, Bettina , Drexler, Hannes C. A. , Brinkmann, Heike , Kremer, Ludmila , Stehling, Martin , Borowski, Marie-Theres , Mildner, Karina , Zeuschner, Dagmar , Zernicka-Goetz, Magdalena , Stemmler, Marc P. , Busch, Karin B. , Vaquerizas, Juan M. and Bedzhov, Ivan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Lima1 is an extensively studied prognostic marker of malignancy and is also considered to be a tumour suppressor, but its role in a developmental context of non-transformed cells is poorly understood. Here, we characterise the expression pattern and examined the function of Lima1 in mouse embryos and pluripotent stem cell lines. We identify that Li...
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Full title
Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism
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TN_cdi_doaj_primary_oai_doaj_org_article_ec59b98c93f041c9b516251c4f4d904c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec59b98c93f041c9b516251c4f4d904c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28139-5
