Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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During infection of macrophages, the pathogenic bacterium
Legionella pneumophila
secretes effector proteins that induce the conversion of the plasma membrane-derived vacuole into an endoplasmic reticulum (ER)-like replicative vacuole. These ER-like vacuoles are ultimately fused with the ER, where the pathogen replicates. Here we show that the...
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Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
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TN_cdi_doaj_primary_oai_doaj_org_article_ec754c6774e2435dac51a43ad70686a2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec754c6774e2435dac51a43ad70686a2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15406
