Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activati...
Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Hypoxia regulates autophagy and nucleotide-binding oligomerization domain receptor, pyrin domain containing (NLRP)3, two innate immune mechanisms linked by mutual regulation and associated to IBD. Here we show that hypoxia ameliorates inflammation during the development of colitis by modulating autophagy and mammalian target of rapamycin (mTOR)/NLR...
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Full title
Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation
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TN_cdi_doaj_primary_oai_doaj_org_article_ec822dd8ef504b80b17abfefcd2b752a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec822dd8ef504b80b17abfefcd2b752a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00213-3
