Berberine is an insulin secretagogue targeting the KCNH6 potassium channel
Berberine is an insulin secretagogue targeting the KCNH6 potassium channel
About this item
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Author / Creator
Zhao, Miao-Miao , Lu, Jing , Li, Sen , Wang, Hao , Cao, Xi , Li, Qi , Shi, Ting-Ting , Matsunaga, Kohichi , Chen, Chen , Huang, Haixia , Izumi, Tetsuro and Yang, Jin-Kui
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Coptis chinensis
is an ancient Chinese herb treating diabetes in China for thousands of years. However, its underlying mechanism remains poorly understood. Here, we report the effects of its main active component, berberine (BBR), on stimulating insulin secretion. In mice with hyperglycemia induced by a high-fat diet, BBR significantly increases...
Alternative Titles
Full title
Berberine is an insulin secretagogue targeting the KCNH6 potassium channel
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ec84125247fe45d184dfac34b2787232
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ec84125247fe45d184dfac34b2787232
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25952-2
