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A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived...

A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ecbbba5bcf1d457aa729dcad33a082c6

A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived Growth Factor-Induced Intracellular Calcium Release

About this item

Full title

A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived Growth Factor-Induced Intracellular Calcium Release

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2019-10, Vol.8 (11), p.1351

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Platelet-derived growth factor (PDGF) signaling is dysregulated in a wide variety of diseases, making PDGF an attractive therapeutic target. However, PDGF also affects numerous signaling cascades essential for tissue homeostasis, limiting the development of PDGF-based therapies that lack adverse side-effects. Recent studies showed that fibroblast-m...

Alternative Titles

Full title

A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived Growth Factor-Induced Intracellular Calcium Release

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ecbbba5bcf1d457aa729dcad33a082c6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ecbbba5bcf1d457aa729dcad33a082c6

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells8111351

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