Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the...
Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
In the adult brain, both neurons and oligodendrocytes can be generated from neural stem cells located within the Sub-Ventricular Zone (SVZ). Physiological signals regulating neuronal versus glial fate are largely unknown. Here we report that a thyroid hormone (T3)-free window, with or without a demyelinating insult, provides a favorable environment...
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Full title
Transient hypothyroidism favors oligodendrocyte generation providing functional remyelination in the adult mouse brain
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TN_cdi_doaj_primary_oai_doaj_org_article_ed0a67c3aa544652b6294e3036301495
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed0a67c3aa544652b6294e3036301495
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.29996
