Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in trip...
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
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Publisher
England: BioMed Central
Journal title
Language
English
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Publisher
England: BioMed Central
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Contents
Triple negative breast cancer (TNBC) easily develops resistance to the first-line drug doxorubicin, because of the high levels of the drug efflux transporter P-glycoprotein (Pgp) and the activation of pro-survival pathways dependent on endoplasmic reticulum (ER). Interfering with these mechanisms may overcome the resistance to doxorubicin, a still...
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Full title
Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_ed0eee255640484a842ee51837285c91
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed0eee255640484a842ee51837285c91
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-018-0967-0
