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A landscape of X-inactivation during human T cell development

A landscape of X-inactivation during human T cell development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed1813ba8f79424fb393f3a3ebc01478

A landscape of X-inactivation during human T cell development

About this item

Full title

A landscape of X-inactivation during human T cell development

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-12, Vol.15 (1), p.10527-14, Article 10527

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Females exhibit a more robust immune response to both self-antigens and non-self-antigens than males, resulting in a higher prevalence of autoimmune diseases but more effective responses against infection. Increased expression of X-linked immune genes in female T cells is thought to underlie this enhanced response. Here we isolate thymocytes from p...

Alternative Titles

Full title

A landscape of X-inactivation during human T cell development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ed1813ba8f79424fb393f3a3ebc01478

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed1813ba8f79424fb393f3a3ebc01478

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-54110-7