Structural basis of dimerization of chemokine receptors CCR5 and CXCR4
Structural basis of dimerization of chemokine receptors CCR5 and CXCR4
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
G protein-coupled receptors (GPCRs) are prominent drug targets responsible for extracellular-to-intracellular signal transduction. GPCRs can form functional dimers that have been poorly characterized so far. Here, we show the dimerization mechanism of the chemokine receptors CCR5 and CXCR4 by means of an advanced free-energy technique named coarse-...
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Full title
Structural basis of dimerization of chemokine receptors CCR5 and CXCR4
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TN_cdi_doaj_primary_oai_doaj_org_article_ed387388cdd649dd94934622d941c9bf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed387388cdd649dd94934622d941c9bf
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42082-z
