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Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed3d8f0c921541cb8291f5f96c64889e

Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Diseases are a manifestation of how thousands of proteins interact. In several diseases, such as cancer and Alzheimer’s disease, proteome-wide disturbances in protein-protein interactions are caused by alterations to chaperome scaffolds termed epichaperomes. Epichaperome-directed chemical probes may be useful for detecting and reversing defective c...

Alternative Titles

Full title

Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ed3d8f0c921541cb8291f5f96c64889e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed3d8f0c921541cb8291f5f96c64889e

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-24821-2

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