MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin...
MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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MDGA molecules can bind neuroligins and interfere with trans-synaptic interactions to neurexins, thereby impairing synapse development. However, the subcellular localization and dynamics of MDGAs, or their specific action mode in neurons remain unclear. Here, surface immunostaining of endogenous MDGAs and single molecule tracking of recombinant MDG...
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MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
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TN_cdi_doaj_primary_oai_doaj_org_article_ed4ed58b731048d6a93d60b138a1317d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed4ed58b731048d6a93d60b138a1317d
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.75233