GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic ex...
GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The passive transport of glucose and related hexoses in human cells is facilitated by members of the glucose transporter family (GLUT, SLC2 gene family). GLUT3 is a high-affinity glucose transporter primarily responsible for glucose entry in neurons. Changes in its expression have been implicated in neurodegenerative diseases and cancer. GLUT3 inhi...
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GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems
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TN_cdi_doaj_primary_oai_doaj_org_article_ed5179664a9e4f51a1594dbab4844691
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed5179664a9e4f51a1594dbab4844691
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-05383-9