Single Cell-Based Vector Tracing in Patients with ADA-SCID Treated with Stem Cell Gene Therapy
Single Cell-Based Vector Tracing in Patients with ADA-SCID Treated with Stem Cell Gene Therapy
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Publisher
United States: Elsevier Limited
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Language
English
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United States: Elsevier Limited
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Clinical improvement in stem cell gene therapy (SCGT) for primary immunodeficiencies depends on the engraftment levels of genetically corrected cells, and tracing the transgene in each hematopoietic lineage is therefore extremely important in evaluating the efficacy of SCGT. We established a single cell-based droplet digital PCR (sc-ddPCR) method c...
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Full title
Single Cell-Based Vector Tracing in Patients with ADA-SCID Treated with Stem Cell Gene Therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_ed70ec7c4d1c4466aa7a2d0b95a82b56
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed70ec7c4d1c4466aa7a2d0b95a82b56
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ISSN
2329-0501
E-ISSN
2329-0501
DOI
10.1016/j.omtm.2017.05.005
