Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Baci...
Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis
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Author / Creator
Ding, Xiumin , Zheng, Zhiming , Zhao, Genhai , Wang, Li , Wang, Han , Yang, Qiang , Zhang, Mengxue , Li, Luyao and Wang, Peng
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Menaquinone-7 (MK-7), which is associated with complex and tightly regulated pathways and redox imbalances, is produced at low titres in Bacillus subtilis. Synthetic biology provides a rational engineering principle for the transcriptional optimisation of key enzymes and the artificial creation of cofactor regeneration systems without regulatory in...
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Full title
Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ed8f2ce0ffc24822b86b1022dfe90ff5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ed8f2ce0ffc24822b86b1022dfe90ff5
Other Identifiers
ISSN
1475-2859
E-ISSN
1475-2859
DOI
10.1186/s12934-022-01823-3
