Efficacy of a novel double-controlled oncolytic adenovirus driven by the Ki67 core promoter and arme...
Efficacy of a novel double-controlled oncolytic adenovirus driven by the Ki67 core promoter and armed with IL-15 against glioblastoma cells
About this item
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Author / Creator
Zhang, Qing , Zhang, Junwen , Tian, Yifu , Zhu, Guidong , Liu, Sisi and Liu, Fusheng
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Glioblastoma (GBM) is an immunosuppressive, highly vascular and devastating malignant brain tumor. Even with progressive combination treatment that includes surgery, radiotherapy, and chemotherapy, the prognosis for GBM patients is still extremely poor. Oncolytic adenovirus (OAd) can specifically replicate in GBM cells, permitting the rapid copy of...
Alternative Titles
Full title
Efficacy of a novel double-controlled oncolytic adenovirus driven by the Ki67 core promoter and armed with IL-15 against glioblastoma cells
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_edbe4880ef0641eeb2d5405c69194a3d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_edbe4880ef0641eeb2d5405c69194a3d
Other Identifiers
ISSN
2045-3701
E-ISSN
2045-3701
DOI
10.1186/s13578-020-00485-1
