Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of ce...
Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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It was previously reported that mRNA expression levels in the prefrontal cortex at old age start to resemble pre-adult levels. Such expression reversals could imply loss of cellular identity in the aging brain, and provide a link between aging-related molecular changes and functional decline. Here we analyzed 19 brain transcriptome age-series datas...
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Gene expression reversal toward pre-adult levels in the aging human brain and age-related loss of cellular identity
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TN_cdi_doaj_primary_oai_doaj_org_article_ededa3881d4b43a9b6f96ce5433f351a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ededa3881d4b43a9b6f96ce5433f351a
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-05927-4
