Regulation of bone homeostasis by MERTK and TYRO3
Regulation of bone homeostasis by MERTK and TYRO3
About this item
Full title
Author / Creator
Engelmann, Janik , Zarrer, Jennifer , Gensch, Victoria , Riecken, Kristoffer , Berenbrok, Nikolaus , Luu, The Vinh , Beitzen-Heineke, Antonia , Vargas-Delgado, Maria Elena , Pantel, Klaus , Bokemeyer, Carsten , Bhamidipati, Somasekhar , Darwish, Ihab S. , Masuda, Esteban , Burstyn-Cohen, Tal , Alberto, Emily J. , Ghosh, Sourav , Rothlin, Carla , Hesse, Eric , Taipaleenmäki, Hanna , Ben-Batalla, Isabel and Loges, Sonja
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The fine equilibrium of bone homeostasis is maintained by bone-forming osteoblasts and bone-resorbing osteoclasts. Here, we show that TAM receptors MERTK and TYRO3 exert reciprocal effects in osteoblast biology: Osteoblast-targeted deletion of MERTK promotes increased bone mass in healthy mice and mice with cancer-induced bone loss, whereas knockou...
Alternative Titles
Full title
Regulation of bone homeostasis by MERTK and TYRO3
Authors, Artists and Contributors
Author / Creator
Zarrer, Jennifer
Gensch, Victoria
Riecken, Kristoffer
Berenbrok, Nikolaus
Luu, The Vinh
Beitzen-Heineke, Antonia
Vargas-Delgado, Maria Elena
Pantel, Klaus
Bokemeyer, Carsten
Bhamidipati, Somasekhar
Darwish, Ihab S.
Masuda, Esteban
Burstyn-Cohen, Tal
Alberto, Emily J.
Ghosh, Sourav
Rothlin, Carla
Hesse, Eric
Taipaleenmäki, Hanna
Ben-Batalla, Isabel
Loges, Sonja
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee00da2c9ae74841a30cb1a635750ba7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee00da2c9ae74841a30cb1a635750ba7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-33938-x
