Effects of the SGLT-2 Inhibitor Canagliflozin on Adenine-Induced Chronic Kidney Disease in Rats
Effects of the SGLT-2 Inhibitor Canagliflozin on Adenine-Induced Chronic Kidney Disease in Rats
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Germany: Cell Physiol Biochem Press GmbH & Co KG
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Language
English
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Publisher
Germany: Cell Physiol Biochem Press GmbH & Co KG
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Contents
SGLT-2 inhibitors have been shown to be nephroprotective in diabetes. Here, we examined if one of these drugs (canagliflozin) could also ameliorate non-diabetic chronic kidney disease (CKD).
CKD was induced in rats by feeding them adenine (0.25%
for 35 days) and canagliflozin (10 or 25 mg/kg, by gavage) was given with or without adenine. Seve...
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Full title
Effects of the SGLT-2 Inhibitor Canagliflozin on Adenine-Induced Chronic Kidney Disease in Rats
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee0fb95949f44bfeb9769e5a7beb1991
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee0fb95949f44bfeb9769e5a7beb1991
Other Identifiers
ISSN
1015-8987
E-ISSN
1421-9778,1015-8987
DOI
10.33594/000000003
