Identification of truncated variants in GLI family zinc finger 3 (GLI3) associated with polydactyly
Identification of truncated variants in GLI family zinc finger 3 (GLI3) associated with polydactyly
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Author / Creator
Wang, Run-Yan , Xiong, Qin , Chang, Si-Hua , Jin, Jie-Yuan , Xiang, Rong , Zeng, Lei and Yu, Fang
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Polydactyly is a prevalent congenital anomaly with an incidence of 2.14 per 1000 live births in China. GLI family zinc finger 3 (GLI3) is a classical causative gene of polydactyly, and serves as a pivotal transcription factor in the hedgehog signaling pathway, regulating the development of the anterior-posterior axis in limbs.
Three pedigrees of...
Alternative Titles
Full title
Identification of truncated variants in GLI family zinc finger 3 (GLI3) associated with polydactyly
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee12dfd404fa46c8ab3d32c0f81a6549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee12dfd404fa46c8ab3d32c0f81a6549
Other Identifiers
ISSN
1749-799X
E-ISSN
1749-799X
DOI
10.1186/s13018-024-04928-0
