A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abd...
A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery
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Author / Creator
de Valk, Kim S. , Handgraaf, Henricus J. , Deken, Marion M. , Sibinga Mulder, Babs G. , Valentijn, Adrianus R. , Terwisscha van Scheltinga, Anton G. , Kuil, Joeri , van Esdonk, Michiel J. , Vuijk, Jaap , Bevers, Rob F. , Peeters, Koen C. , Holman, Fabian A. , Frangioni, John V. , Burggraaf, Jacobus and Vahrmeijer, Alexander L.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Iatrogenic injury of the ureters is a feared complication of abdominal surgery. Zwitterionic near-infrared fluorophores are molecules with geometrically-balanced, electrically-neutral surface charge, which leads to renal-exclusive clearance and ultralow non-specific background binding. Such molecules could solve the ureter mapping problem by provid...
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Full title
A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery
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TN_cdi_doaj_primary_oai_doaj_org_article_ee290759ae054fec9dc8492256ab1fea
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee290759ae054fec9dc8492256ab1fea
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11014-1
