CircHIF1A induces cetuximab resistance in colorectal cancer by promoting HIF1α-mediated glycometabol...
CircHIF1A induces cetuximab resistance in colorectal cancer by promoting HIF1α-mediated glycometabolism alteration
About this item
Full title
Author / Creator
Geng, Yiting , Zheng, Xiao , Zhang, Dachuan , Wei, Shanshan , Feng, Jun , Wang, Wei , Zhang, Luo , Wu, Changping and Hu, Wenwei
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
More information
Scope and Contents
Contents
Epidermal growth factor receptor (EGFR)-targeted therapy is an important treatment for RAS wild-type metastatic colorectal cancer (mCRC), but the resistance mechanism remains unclear. Here, the differential expression of circRNAs between Cetuximab sensitive and resistant cell lines was analyzed using whole-transcriptome sequencing. We identified th...
Alternative Titles
Full title
CircHIF1A induces cetuximab resistance in colorectal cancer by promoting HIF1α-mediated glycometabolism alteration
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee4d73e8c2ab48c68bc10be1ac025155
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee4d73e8c2ab48c68bc10be1ac025155
Other Identifiers
ISSN
1745-6150
E-ISSN
1745-6150
DOI
10.1186/s13062-024-00478-x
