Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
About this item
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Author / Creator
Vitiello, Pietro Paolo , Martini, Giulia , Mele, Luigi , Giunta, Emilio Francesco , De Falco, Vincenzo , Ciardiello, Davide , Belli, Valentina , Cardone, Claudia , Matrone, Nunzia , Poliero, Luca , Tirino, Virginia , Napolitano, Stefania , Della Corte, Carminia , Selvaggi, Francesco , Papaccio, Gianpaolo , Troiani, Teresa , Morgillo, Floriana , Desiderio, Vincenzo , Ciardiello, Fortunato and Martinelli, Erika
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Despite the advancements in new therapies for colorectal cancer (CRC), chemotherapy still constitutes the mainstay of the medical treatment. For this reason, new strategies to increase the efficacy of chemotherapy are desirable. Poly-ADP-Ribose Polymerase inhibitors (PARPi) have shown to increase the activity of DNA damaging chemotherapeutics used...
Alternative Titles
Full title
Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
Authors, Artists and Contributors
Author / Creator
Martini, Giulia
Mele, Luigi
Giunta, Emilio Francesco
De Falco, Vincenzo
Ciardiello, Davide
Belli, Valentina
Cardone, Claudia
Matrone, Nunzia
Poliero, Luca
Tirino, Virginia
Napolitano, Stefania
Della Corte, Carminia
Selvaggi, Francesco
Papaccio, Gianpaolo
Troiani, Teresa
Morgillo, Floriana
Desiderio, Vincenzo
Ciardiello, Fortunato
Martinelli, Erika
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee6656f7232f43be80a2f6cd65a8083d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee6656f7232f43be80a2f6cd65a8083d
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-020-01811-8
