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TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss

TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee680a85071948b39c307816e8828d24

TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss

About this item

Full title

TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss

Publisher

England: BioMed Central

Journal title

Cancer cell international, 2021-04, Vol.21 (1), p.223-223, Article 223

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

To investigate the effect of TriBAFF-CAR-T cells on hematological tumor cells.
TriBAFF-CAR-T and CD19-CAR-T cells were co-cultured with BAFFR-bearing B-cell malignancies at different effector/target ratios to evaluate the anti-tumor effects. In vivo, TriBAFF-CAR-T and CD19-CAR-T cells were intravenously injected into Raji-luciferase xenograft mi...

Alternative Titles

Full title

TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ee680a85071948b39c307816e8828d24

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee680a85071948b39c307816e8828d24

Other Identifiers

ISSN

1475-2867

E-ISSN

1475-2867

DOI

10.1186/s12935-021-01923-x

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