TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss
TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss
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Author / Creator
Li, Guangchao , Zhang, Qing , Liu, Zhi , Shen, Huijuan , Zhu, Yangmin , Zhou, Zhao , Ding, Wen , Han, Siqi , Zhou, Jie , Ou, Ruiming , Luo, Min and Liu, Shuang
Publisher
England: BioMed Central
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
To investigate the effect of TriBAFF-CAR-T cells on hematological tumor cells.
TriBAFF-CAR-T and CD19-CAR-T cells were co-cultured with BAFFR-bearing B-cell malignancies at different effector/target ratios to evaluate the anti-tumor effects. In vivo, TriBAFF-CAR-T and CD19-CAR-T cells were intravenously injected into Raji-luciferase xenograft mi...
Alternative Titles
Full title
TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee680a85071948b39c307816e8828d24
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee680a85071948b39c307816e8828d24
Other Identifiers
ISSN
1475-2867
E-ISSN
1475-2867
DOI
10.1186/s12935-021-01923-x