PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elect...
PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elective neurointervention: A prospective single-center cohort study
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Author / Creator
Koji Tanaka , Shoji Matsumoto , Gulibahaer Ainiding , Ichiro Nakahara , Hidehisa Nishi , Tetsuya Hashimoto , Tsuyoshi Ohta , Nobutake Sadamasa , Ryota Ishibashi , Masanori Gomi , Makoto Saka , Haruka Miyata , Sadayoshi Watanabe , Takuya Okata , Kazutaka Sonoda , Junpei Koge , Kyoko M Iinuma , Konosuke Furuta , Izumi Nagata , Keitaro Matsuo , Takuya Matsushita , Noriko Isobe , Ryo Yamasaki and Jun-Ichi Kira
Publisher
Public Library of Science (PLoS)
Journal title
Language
English
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Publisher
Public Library of Science (PLoS)
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Scope and Contents
Contents
Background and purposeThe impact of the paraoxonase-1 (PON1) polymorphism, Q192R, on platelet inhibition in response to clopidogrel remains controversial. We aimed to investigate the association between carrier status of PON1 Q192R and high platelet reactivity (HPR) with clopidogrel in patients undergoing elective neurointervention.MethodsPost-clop...
Alternative Titles
Full title
PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elective neurointervention: A prospective single-center cohort study
Authors, Artists and Contributors
Author / Creator
Shoji Matsumoto
Gulibahaer Ainiding
Ichiro Nakahara
Hidehisa Nishi
Tetsuya Hashimoto
Tsuyoshi Ohta
Nobutake Sadamasa
Ryota Ishibashi
Masanori Gomi
Makoto Saka
Haruka Miyata
Sadayoshi Watanabe
Takuya Okata
Kazutaka Sonoda
Junpei Koge
Kyoko M Iinuma
Konosuke Furuta
Izumi Nagata
Keitaro Matsuo
Takuya Matsushita
Noriko Isobe
Ryo Yamasaki
Jun-Ichi Kira
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ee85d159b18f4b65aca124675715358b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee85d159b18f4b65aca124675715358b
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E-ISSN
1932-6203
DOI
10.1371/journal.pone.0254067