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PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elect...

PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elect...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee85d159b18f4b65aca124675715358b

PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elective neurointervention: A prospective single-center cohort study

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Full title

PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elective neurointervention: A prospective single-center cohort study

Publisher

Public Library of Science (PLoS)

Journal title

PloS one, 2021-01, Vol.16 (8), p.e0254067

Language

English

Formats

Publication information

Publisher

Public Library of Science (PLoS)

More information

Scope and Contents

Contents

Background and purposeThe impact of the paraoxonase-1 (PON1) polymorphism, Q192R, on platelet inhibition in response to clopidogrel remains controversial. We aimed to investigate the association between carrier status of PON1 Q192R and high platelet reactivity (HPR) with clopidogrel in patients undergoing elective neurointervention.MethodsPost-clop...

Alternative Titles

Full title

PON1 Q192R is associated with high platelet reactivity with clopidogrel in patients undergoing elective neurointervention: A prospective single-center cohort study

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Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ee85d159b18f4b65aca124675715358b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee85d159b18f4b65aca124675715358b

Other Identifiers

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0254067

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