Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and...
Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice
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England: BioMed Central
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Language
English
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England: BioMed Central
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Vascular dysregulation and cholinergic basal forebrain degeneration are both early pathological events in the development of Alzheimer’s disease (AD). Acetylcholine contributes to localised arterial dilatation and increased cerebral blood flow (CBF) during neurovascular coupling via activation of endothelial nitric oxide synthase (eNOS). Decreased...
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Loss of cholinergic innervation differentially affects eNOS-mediated blood flow, drainage of Aβ and cerebral amyloid angiopathy in the cortex and hippocampus of adult mice
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TN_cdi_doaj_primary_oai_doaj_org_article_ee868e90148f4c68b184f20760ef4db9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ee868e90148f4c68b184f20760ef4db9
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-020-01108-z
